2021/086 ISOLATED HYPERBILIRUBINEMIA conjugated (direct hyperbilirubinemia) or unconjugated (indirect hyperbilirubinemia)? An increase in unconjugated bilirubin in serum results from overproduction, impairment of uptake, or impaired conjugation of bilirubin. An increase in conjugated bilirubin is due to decreased excretion into the bile ductules or leakage of the pigment from hepatocytes into serum. 2021. 8. 18. ELEVATED ALKALINE PHOSPHATASE In patients with cholestasis, the alkaline phosphatase is typically elevated to at least four times the upper limit of normal. The gamma-glutamyl transpeptidase (GGT) may also be elevated in the setting of cholestasis. Patients with a predominantly cholestatic pattern typically undergo a right upper quadrant ultrasound to further characterize the cholestasis as intrahepatic or extrahepatic; the .. 2021. 8. 18. 이전 1 2 다음