ISOLATED HYPERBILIRUBINEMIA

 conjugated (direct hyperbilirubinemia) or unconjugated (indirect hyperbilirubinemia)?

 

An increase in unconjugated bilirubin in serum results from overproduction, impairment of uptake, or impaired conjugation of bilirubin. An increase in conjugated bilirubin is due to decreased excretion into the bile ductules or leakage of the pigment from hepatocytes into serum.